Luciferase Cell Lines

Luciferase stable cell lines (i.e. luciferase labeled cell lines) constitutively express firefly luciferase. Luciferase can catalyze the oxidation of luciferin. In the process of luciferin oxidation, it will emit biological fluorescence, and the luminous intensity can be accurately quantified.

Luciferase cell lines (luc cells) have become an important tool in the life sciences, showing great potential especially in disease modeling, drug screening and monitoring of therapeutic effects. By stably expressing luciferase protein in tumor cells, researchers can track the distribution, spread and migration of tumor cells in real time in vivo. This is crucial for studying the mechanisms of tumor aggressiveness and metastasis. Luciferase cells can also be used for high-throughput screening of anti-tumor drugs, where changes in luciferase activity are measured to assess the effect of drugs on tumor cell growth inhibition.

Why use luciferase labeled cell line?

After luciferase cells are implanted into model animals, the signal can be detected as early as 1 day after tumor cell injection, while conventional fluorescence-expressing tumors can not be detected until 7 days later. Pre-made Luc cell lines save you time, labor, and experimental costs in constructing a luciferase stable cell line. All luciferase cells are characterized by luciferase activity for excellent imaging.

Product feature: Vitro Biotech provides low-passage Luciferase stable cell lines. This portfolio are tested for luciferase activity and have good tumorigenicity. All cell lines are STR profiled, in good viability, and luciferase stably expressed.

If your preferred luciferase cell line is not on the list, please contact us to get a quote for the stable cell line customization service. A luciferase labeled cell line can be obtained as soon as 5 weeks.