Knockout Cell Lines

Knockout cell lines (KO cells) help to overcome the challenge of obtaining "real controls" during research and development, and enable reliable validation of genotype-phenotype relationships. KO cell lines are a powerful tool for investigating disease mechanisms, and are therefore suitable for validation of potential therapeutic targets. The CRISPR revolution has facilitated the rapid development of gene-edited cells in a variety of tests and assays, thus simplifying drug discovery and trial development.

Ready-to-use KO cell lines save researchers' time in cell model generation, which typically takes 2-4 months for KO cell construction. Pre-made KO cells allow direct study for the gene of interest. Also, this portfolio of cell lines greatly helps you avoid the risk of cell model construction failure.

This portfolio of in-stock KO cell lines are edited on the most commonly used cell lines, such as HEK293, A549, HeLa, HCT116, THP-1, HepG2, etc. These off-shelf knockout cell lines are gene knockout homozygous clones validated by Sanger sequencing. It can be used in many research scenarios such as gene function study, antibody validation, negative control of drug discovery, etc. Welcome to explore your ideal Knockout cell lines.

Product feature: These KO cell lines are off-shelf and ready to use. They are in low passage and in good viability. All knockout cell lines are STR profiled and tested for mycoplasma.

If your preferred KO cell line is not on the list, please contact us to get a quote for the gene knockout cell line customization service. The target KO cell line can be obtained as soon as 8 weeks.