Drug Resistant Research

Drug-resistant cell lines are constructed by using an in vitro low concentration gradient increment combined with a high-dose intermittent shock method to induce tumor cells to become resistant to a specific drug. Drug resistance is usually not caused by a single factor, but is the result of the interaction of multiple factors. Using drug-resistant cells, it is possible to explore these complex networks, such as protein-protein interactions, changes in metabolic pathways, etc., which contribute to a comprehensive understanding of the biological basis of drug resistance.

Drug-resistant cells are an important tool for studying the mechanisms of drug resistance in tumor cells or pathogens. By comparing the response of drug-resistant and non-drug-resistant cells to a particular drug, it is possible to identify molecular markers, alterations in gene expression or changes in signaling pathways that lead to drug resistance. Drug-resistant cells can be used to screen and evaluate the effectiveness of drugs during the development of new medicines. By testing drug candidates against drug-resistant cells, more effective drugs can be screened for their ability to overcome known resistance mechanisms.

Vitro Biotech offers various drug resistant cell lines, including Docetaxel, Adriamycin (doxorubicin), Tamoxifen, Faslodex, Casodex, Vincristine, Cisplatinum. Help your research to discover the resistance mechanisms.