Luc Imaging

Vitro Biotech's Luciferase Imaging series include Luciferase cell lines, Luc-GFP cell lines, Luciferase Lentivirus, and Luciferase Reagents. The products provided by Vitro Biotech have been comprehensively validated, and guarantee good viability and mycoplasma free. Feel free to browse our product list. To get a quote, please contact info@vitrobiotech.com

Luciferase Cell List
Luciferase cell lines (luc cell lines) have become an important tool in the life sciences, showing great potential especially in disease modeling, drug screening and monitoring of therapeutic effects. By stably expressing luciferase protein in tumor cells, researchers can track the distribution, spread and migration of tumor cells in real time in vivo. This is crucial for studying the mechanisms of tumor aggressiveness and metastasis. Luciferase cells can also be used for high-throughput screening of anti-tumor drugs, where changes in luciferase activity are measured to assess the effect of drugs on tumor cell growth inhibition.
After luciferase cells are implanted into model animals, the signal can be detected as early as 1 day after tumor cell injection, while conventional fluorescence-expressing tumors can not be detected until 7 days later. Pre-made Luc cell lines save you time, labor, and experimental costs in constructing a luciferase stable cell line. All luciferase cells are characterized by luciferase activity for excellent imaging.

Luc-GFP Cell List
Luc-GFP cell lines are dual labeled with luciferase and GFP. Luciferase allows for highly sensitive, non-invasive detection of cancer cell growth and progression in vivo as early as one day after injection. In addition, GFP expression can be used for in vivo tumor monitoring without the need for substrates, as well as for in vitro observation and fluorescence immunocytochemistry experiments.
Luc-GFP cells can be applied to characterize tumor cells in vitro using biochemical and genetic methods. As well as monitoring tumor growth, progression and metastasis in vivo in response to various environmental stimuli, drugs and other treatments. This portfolio is combining the advantages of luciferase cells and fluorescent cells, cost-effective!

Luciferase Lentivirus
Luciferase is a general term for a class of oxidative enzymes used for bioluminescence, the most commonly used luciferase are firefly luciferase (F-Luc) (Photinus pyralis), Renilla luciferase (R-Luc), Nano-luciferase(N-Luc), Luc1, and Luc2. Luc1 substrate itself will be a bit autoluminescent. Its wave band is longer, so it will be slightly diffuse compared to Luc2, but the signal is much higher than conventional F-Luc. Luc2 has a high resolution for in vivo imaging, and even a few tumor cells can be detected. 
Need luciferase lentivirus to make stable cell lines or inject animals? Vitro Biotech offers a variety of luciferase lentiviruses that are high titer, ultra-purified, and can be injected directly into model animals such as mice and rats.

Luciferase Reagents
For different kinds of luciferase, we provide various types of substrates, such as Luc2 substrate, Luc1 substrate, CycLuc 1, D-Luciferin sodium, D-Luciferin, Coelenterazine, luciferase assay kit, and dual luciferase assay kit.