Vitro Biotech's CRISPR Cell Lines & Screen series include KO cell lines, Cas9 stable cell lines, and CRISPR screen libraries. The cell lines provided by Vitro Biotech have been comprehensively validated, and guarantee low passage, good viability, and mycoplasma free. CRISPR libraryies are NGS tested, and guarantee coverage ≥99% and uniformity <10. Feel free to browse our product list. To get a quote, please contact info@vitrobiotech.com
KO Cell List
Knockout cell lines (KO cells) help to overcome the challenge of obtaining "real controls" during research and development, and enable reliable validation of genotype-phenotype relationships. KO cell lines are a powerful tool for investigating disease mechanisms, and are therefore suitable for validation of potential therapeutic targets. The CRISPR revolution has facilitated the rapid development of gene-edited cells in a variety of tests and assays, thus simplifying drug discovery and trial development.
Ready-to-use KO cell lines save researchers' time in cell model generation, which typically takes 2-4 months for KO cell construction. Pre-made KO cells allow direct study for the gene of interest. Also, this portfolio of cell lines greatly helps you avoid the risk of cell model construction failure.
Cas9 Stable Cell List
Need to construct gene editing cell models by yourself? Cas9 expressing cell lines can greatly facilitate researchers who need to build their own gene-editing cell models. Using Cas9 stable cell line to generate a gene-editing cell model can greatly improve the success rate of the experiment, and can be widely used in the construction of cell models for gene knockout, point mutation, markers knock-in and other site-targeted genome modifications.
Need to perform CRISPR screening? A cell line that efficiently expresses Cas9 is the key to reliable CRISPR screening. Our Cas9 cell stock has been characterized by editing efficiency, which can save at least one month's time of constructing the Cas9 stable cell line!
CRISPR Screen Libraries
Need to perform CRISPR screening? Pre-made CRISPR library can accelerate your screening process. Generally a chip-based synthesis of library will take at least 2 month. In this portfolio, we provide 100ug library plasmids, which can produce 1*10^8 TU lentivirus, which satisfy the needs of most CRISPR screening programs. All libraries in stock are provided with NGS QC reports, and guarantee coverage ≥99% and uniformity <10.
New to CRISPR screen? Vitro Biotech offers lentivirus libraries for direct screening, saving at least two weeks of virus packaging. Get started straight away!